ZO Skin Health

ZO Skin Health Daily Power Defense

1
Skip to product information
ZO Skin Health

ZO Skin Health Daily Power Defense

ZO Skin Health Daily Power Defense for daily antioxidant protection - Vos Collection
1/7
ZO Skin Health Daily Power Defense

ZO Skin Health

ZO Skin Health Daily Power Defense

Free shipping on orders over $200.00.

Our best-selling antioxidant serum strengthens skin's protective barrier and defends against the environmental stressors that speed up aging, so skin stays hydrated, calm, and resilient. The daily-defense foundation of healthy, youthful skin.

Clinically tested | Free of Paraben, SLS, SLES, Phthalates, and Gluten

Texture

Serum

Suited For

Normal to dry skin

Key Features

- Defends skin against oxidative damage from free radicals
- Visibly reduces signs of premature aging
- Supports skin barrier restoration + extended skin hydration
- Supports continuously healthy skin

Concerns

Environmental skin aging
Radiant skin with clear complexion - Vos Collection

How to

01
Apply to clean, dry skin AM and PM.

Application

Supports skin barrier restoration + extended skin hydration.Visibly reduces signs of premature aging

Texture

Lightweight serum

Build a routine

Better together

Add this curated product to your routine to complement and enhance your results. Designed to work seamlessly together, it helps create a more balanced, effective regimen.

ZO Skin Health Growth Factor Serum by Zein Obagi MD - Vos Collection
New Arrival

ZO Skin Health Growth Factor Serum

ZO Skin Health Growth Factor Serum
$245.00
Glowing mature woman with radiant skin, natural beauty, healthy complexion

Trusted Results

96%

of participants said skin feels less dry within 15 minutes

84%

of participants said skin feels soothed and it stays hydrated throughout the day

92%

of participants said skin appears healthier by week 2

92%

of participants said skin maintain visual uniformity throughout the day by week 4

Before

Smooth skin after using SkinCeuticals antioxidant serum - Vos Collection

After

Smooth, radiant skin after using medical-grade skincare - Vos Collection

A 12-week independent, third-party clinical study of 38 subjects to assess the efficacy potential of Daily Power Defense. Subjects represent females, ages 47–70, with Fitzpatrick skin types I–IV. Supported with use of Gentle Cleanser and Sunscreen + Primer Broad-Spectrum SPF 30 during the study.

Key ingredients

ZORRS

ZO's Retinol Reaction Support System — a blend of soothing and barrier ingredients that reduces the initial irritation of retinol use.

ZPOLY / ZPRO

ZO's delivery technologies that enhance active ingredient stability, skin penetration, and tolerance in their professional-grade formulations.

MICROCOCCUS LYSATE / ARABIDOPSIS EXTRACT

A UV-resistant microorganism extract containing DNA repair enzymes that help correct UV-induced cellular damage in skin.

ZO Skin Health Daily Power Defense

You might also like

The redness & sensitivity edit

Doctor Approved

FAQS

We got you

ZO Daily Power Defense is an advanced antioxidant serum that supports cellular DNA repair, neutralizes free radicals, and reinforces the skin's barrier integrity.

Unlike basic Vitamin C serums, Daily Power Defense utilizes specialized enzymes (Ultrasomes and Roxisomes) along with retinol and antioxidants to actively repair DNA damage.

YOUR VOS TREATMENT

Positive Aging – Individually curated strategies to keep you looking and feeling your best.

  • 5 stars: 3 (100%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
S
Stephanie M.

Great communication

L
Lorraine C.

I love the day defence I’ve waited for awhile it was out of stock

R
Renee S.

I really like this product, ZO Daily Power Defense is an excellent daily antioxidant serum that focuses on strengthening the skin barrier while defending against environmental damage. The formula is lightweight, well-tolerated, and works beautifully alongside corrective treatments.